热淋清联合左氧氟沙星治疗慢性细菌性前列腺炎的临床效果及治疗安全性评价
[摘要]目的 探究热淋清联合左氧氟沙星在治疗慢性细菌性前列腺炎中的临床效果，并对其治疗安全性进行评价。方法 选取2015年5月～2017年5月我院收治的100例慢性前列腺炎患者作为研究对象，采用随机数字表法将其分为对照组和研究组，每组各50例。对照组患者采用左氧氟沙星治疗，研究组患者采用热淋清联合左氧氟沙星治疗。比较两组患者的治疗效果、前列腺液白细胞指数（EPS-WBC）、前列腺炎症指数（CPSI）以及不良反应发生情况。结果 研究组患者的治疗总有效率（98.00%）高于对照组（78.00%），差异有统计学意义（P<0.05）。治疗后，研究组患者的EPS-WBS和CPSI显著低于对照组，差异有统计学意义（P<0.05）。两组患者的不良反应发生率比较，差异无统计学意义（P>0.05）。结论 热淋清联合左氧氟沙星治疗慢性细菌性前列腺炎具有显著疗效，能够改善患者的临床症状，且不良反应较少，值得在临床上推广。
[关键词]热淋清；左氧氟沙星；慢性细菌性前列腺炎；治疗总有效率；不良反应
[中图分类号] R697.33 [文献标识码] A [文章编号] 1674-4721（2018）2（b）-0132-03
Evaluation of clinical effect and therapeuticsafety of Relinqing combined with Levofloxacin in the treatment of chronic bacterial prostatitis
CHEN Yi-de ZHANG Yong-ke LONG Qi SONG Shao-kang
Department of Urology，the People′s Hospital in Gaoming District，Guangdong Province，Foshan 528500，China
[Abstract]Objective To explore the clinical effect of Relinqing combined with Levofloxacin in thetreatment of chronic bacterial prostatitis and evaluate its therapeutic safety.Methods From May 2015 to May 2017，100 patients diagnosed as chronic bacterial prostatitis treated in our hospital were selected as subjects.By a random number table mathod，they were evenly divided into research group and control group，50 cases in each group.The patients in the control group was treated with Levofloxacin，while the research group was treated wuth Relinqing combined with Levofloxacin.The treatment effect，the white blood cell index of the prostatic fluid （EPS-WBC），the prostate inflammation index （CPSI） and the incidence of adverse reactions of the two groups were compared.Results The total effective rate of the patients in the study group （98.00%） was higher than that in the control group （78.00%），and the difference was statistically significant （P<0.05）.After treatment，the EPS-WBS and CPSI of the study group were significantly lower than those in the control group，and the difference was statistically significant （P<0.05）.There was no significant difference in the incidence of adverse reactions between the two groups （P>0.05）.Conclusion Combination of Relinqing and Levofloxacin obtains a remarkable effect on treating chronic bacterial prostatitis by improving patients′ clinical symptoms in few adverse reactions，which is worthy of clinical promotion.
[Key words]Relinqing；Levofloxacin；Chronic bacterial prostatitis；The total effective rate；Adverse reaction
慢性细菌性前列腺炎在临床上较常见的泌尿生殖疾病，多发于中年男性，但是目前对其发病机制尚未明确[1]。细菌性前列腺炎多是由于机体受到病原体逆行感染所致，其中病原菌多为葡萄球菌属，具有反复发作、治疗周期长等特点，严重影响患者的生活质量[2]。其临床症状表现为尿频、尿急、尿路感染以及尿潴留等，临床上常采用白细胞计数和影像学检查进行诊断[3-4]。目前对于该病的治疗，初期采用抗生素初步改善病情，后运用α-受体阻断剂和热敷按摩等方法来改善尿路水肿，严重者需采用手术进行治疗[5-6]。本研究选取我院收治的100例慢性前列腺炎患者作为研究对象，探究熱淋清联合左氧氟沙星治疗慢性细菌性前列腺炎中的临床效果和安全性，现报道如下。