银翘散合半夏泻心汤加减治疗咽食管反流性咽炎40例临床观察

　　【摘要】 目的：探討银翘散合半夏泻心汤加减治疗咽食管反流性咽炎的临床效果。方法：选取2015年
　　10月-2017年3月本院收治的咽食管反流性咽炎患者40例，按照随机数字表法分为对照组与试验组，各20例。对照组采用常规西医治疗，试验组采用银翘散合半夏泻心汤加减治疗。比较两组治疗效果、不良反应、治疗前后的反流症状指数量表（reflux symptom index，RSI）和反流检查计分量表（reflux finding score，RFS）评分。结果：试验组治疗总有效率为95.00%，高于对照组的70.00%（P<0.05）；治疗后，试验组患者RSI评分中声嘶或发声问题、清喉和咽喉黏液增多等各维度评分均低于对照组，RFS评分中声门下水肿、喉室消失和红斑、充血等各维度得分均低于对照组，比较差异均有统计学意义（P<0.05）；试验组不良反应发生率为10.00%，明显低于对照组的45.00%（P<0.05）。结论：银翘散合半夏泻心汤加减治疗咽食管反流性咽炎疗效显著，可有效缓解其临床症状，解除患者痛苦，且用药安全性高，值得在临床推广应用。
　　【关键词】 银翘散； 半夏泻心汤； 咽食管反流性咽炎； 加减； 疗效
　　Clinical Observation on Yinqiao Powder Combined Banxia Xiexin Decoction in Treatment of 40 Patients with Pharyngoesophageal Reflux Pharyngitis/CAO Zhi，LIU Yuanxian，LIU Xia，et al.//Medical Innovation of China，2018，15（07）：073-077
　　【Abstract】 Objective：To investigate the clinical effect of Yinqiao Powder combined Banxia Xiexin Decoction in treatment of pharyngoesophageal reflux pharyngitis.Method：A total of 40 patients with pharyngoesophageal reflux pharyngitis in our hospital from October 2015 to March 2017 were selected，according to the random number table method，they were divided into control group and experimental group，20 cases in each group.The control group orally took the conventional western medicine，and experimental group were treated with Yinqiao Powder combined Banxia Xiexin Decoction.The therapeutic effects，adverse reactions，the reflux symptom index（RSI） and reflux finding score（RFS） before and after treatment between two groups were compared.Result：The total effective rate of treatment in experimental group was 95.00%，was higher than 70.00% of control group（P<0.05）.After treatment，the RSI scores of hoarseness or vocal problems，clear throat，laryngic mucus increase and the scores of each dimension in experimental group were lower than those of control group，the RFS score of subglottic edema，laryngeal chamber disappearance，erythema and hyperemia and the scores of each dimension were all lower than those of control group，the differences were statistically significant（P<0.05）.The incidence of adverse reactions in experimental group was 10.00%，which was significantly lower than 45.00% of control group（P<0.05）.Conclusion：Yinqiao Powder combined Banxia Xiexin Decoction is effective in treatment of pharyngoesophageal reflux pharyngitis，can effectively relieve the clinical symptoms，relieve the sufferings of the patients，and have high safety in drug use，which is worth popularizing in clinical application.
　　【Key words】 Yinqiao Powder； Banxia Xiexin Decoction； Pharyngoesophageal reflux pharyngitis； Modified； Clinical effect